FINAL PROGRAMME

BASIC SCIENCE -
YOUNG INVESTIGATOR FORUM





HALL MUSEUM 4 09:00 - 17:30

European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) in collaboration
with European Kidney Research Association (EKRA) and International Union of Physiological Sciences (IUPS)

 

Kidney Transport Regulation

Lessons from rare disorders: the Bardet-Biedl syndrome
Philip L. Beales, London, United Kingdom

Regulation of localization and function of Polycystin-2
M. Köttgen, T. Benzing, R. Tauber, B. Buchholz, D. Steffl, C. Kopp, T. Simmen, T.B. Huber, B. Schermer, G. Thomas, E. Kim, G. Walz, Freiburg, Germany

Defective coupling of apical PTH receptors to phosholipase C and loss of PTH induced internalization of NaPi-IIa in NHERF1 knock out mice
P. Capuano, D. Bacic, M. Roos, S.M. Gisler, J. Biber, B. Kaissling, E.J. Weinman, C.A. Wagner, H. Murer, Zurich, Switzerland

Enhanced passive Ca2+ reabsorption and reduced Mg2+ channel abundance explains thiazide-induced hypocalciuria and hypomagnesemia
T. Nijenhuis, A.W.C.M. van der Kemp, J. Loffing, J.G.J. Hoenderop, R.J.M. Bindels, Nijmegen, the Netherlands

Early-aldosterone regulated gene products and the ubiquitin connection
François Verrey, Zurich, Switzerland

Identification of early aldosterone-regulated mRNAs in mouse ASDN using Affymetrix GeneChips
P. Fakitsas, G. Adam, A. Patrignani, U. Wagner, R. Warth, F. Verrey, Zurich, Switzerland

Role of USP10 (Ubiquitin Specific Protease 10), a vasopressin induced deubiquitylating enzyme (DUB) in the cortical collecting duct
S. Boulkroun, F. Terranova, G. Willemin, O. Staub, Lausanne, Swizerland

 

Blood Vessels-Glomeruli

Signaling at the slit diaphragm: solving the puzzle
Thomas Benzing, Freiburg, Germany

TNFαa inhibits renin gene expression and induces reversible phenotype changes in renin producing cells
V. Todorov, A. Kurtz, Regensburg, Germany

Podocyte-specific autoreactive T cells induce a periglomerular mononuclear infiltrate of dendritic cells and mediate kidney damage
F. Reichel, E.E. Hamilton-Williams, S. Quaggin, F. Eitner, J. Floege, H.J. Gröne, C. Kurts, Bonn, Germany

Vascular endothelial growth factor and angiopoietin-1 alter the ultrafiltration coefficient (LpA) of mammalian glomeruli
A.H.J. Salmon, D.O. Bates, S.J. Harper, Bristol, United Kingdom

Pituitary adenylate cyclase activating-polypeptide (PACAP) is a potent stimulator of renin secretion
F. Schweda, A. Kurtz, Regensburg, Germany

 

Kidney pathology, transplants and protection

YB-1 functions as main regulator of RANTES expression in acute and chronic renal transplant rejection
B.C. Frye, U. Raffetseder, C. Weber, M. Kretzler, J. Floege, P.R. Mertens, Aachen, Germany

Inhibition of mTOR attenuates hypoxic gene regulation in renal cells
K. Knaup, A. Weidemann, K. Jozefowski, J.S. Jürgensen, K.-U. Eckardt, M. Wiesener, Erlangen, Germany

Genome-wide transcriptomic analysis identifi es gene expression signature of NF-kB pathway activation in progressive human diabetic nephropathy
Y. Yasuda, H. Schmid, A. Boucherot, F. Eichinger, B. Brunner, D. M. Sadlier, A. Henger, A. Nitsche, M. Bleich, C.D. Cohen, P. Doran, H.R. Brady, H.J. Groene, D. Schloendorff, P.J. Nelson, M. Kretzler for the ERCB-Consortium, Munich, Germany

 

Posters

 

Kidney Transport Regulation

1. Cross talk among prolactin and dopamine in renal tubular cells
S. Crambert, F. Ibarra, P. Hansell, U. Holtback, Stockholm, Sweden

2. A steady-state kinetic characterization of the mouse B0AT1 sodium-dependent neutral amino acid transporter
V. Makrides, S.M.R. Camargo, L.V. Virkki, I.C. Forster, F. Verrey, Zurich, Switzerland

 

Blood Vessels-Glomeruli

3. Vascular endothelial growth factor (VEGF) induces endothelial remodelling and increased permeability via p38
C. Bodor, A. Masszi, E. Herczenik, L. Cervenák, L. Rosivall, Budapest, Hungary

4. Reconstruction of Bowman's space shows three subdivisions in which perfusion pressure can induce a complex rapid podocytic response
C.R. Neal, P.R. Muston, E. Bell, H. Crook, D.O. Bates, S.J. Harper, Bristol, United Kingdom

 

Kidney pathology, transplants and protection

 

5. Fetuin-A modulates monocyte infl ux and TGF-b expression in experimental renal fi brosis
T. Krüger, R. Westenfeld, V. Brandenburg, R. Smeets, C. Schaefer, S. Stojanov, J. Floege, W. Jahnen-Dechent, M. Ketteler, Aachen, Germany

6. Characterization of diabetic nephropathy by urinary proteomic analysis: identifi cation of biomarker for earlier diagnostic
H. Dihazi, M. Meyer, G.A. Müller, F. Strutz, Goettingen,Germany

7. Heat shock protein 60 is released in nephrotoxic glomerulonephritis and aggravates disease: a novel mechanism of progression of kidney disease
A. Lang, F. Reichel, D. Benke, F. Eitner, D. Engel, E. Hamilton-Williams, M. Breloer, A. von Bonin, J. Floege, C. Kurts, Aachen, Germany

8. Kidney apoptotic changes in patients with type 2 diabetic nephropathy and early or late clinical impairment
M.T. Gandolfo, D. Verzola, F. Gianiorio, B. Villaggio, F. Lauria, M.P. Rastaldi, F. Ferrario, M. Miji, G. Deferrari, G. Garibotto, Genoa, Italy

9. Catecholamine pretreatment inhibits cold storage related damages in endothelial integrity in human endothelial cells
P.T. Brinkkoetter, G. Beck, F.J. van der Woude, B.A. Yard, Mannheim, Germany

10. Preconditional induction of HIF by carbon monoxide ameliorates ischemic acute renal failure
W.M. Bernhardt, S. Kany, V. Campean, J.S. Jurgensen, A. Weidemann, C. Warnecke, C. Willam, U. Frei, K. Amann, M.S. Wiesener K.-U. Eckardt, Berlin, Germany

11. Mitochondrial protection of MDCK cells during metabolic inhibition: in situ mitochondrial Na+ measurements using CoroNa Red
S. Baron, A. Caplanusi, I. Smets, M. VandeVen, M. Ameloot, P. Steels, Diepenbeek, Belgium